Dextrose Prolotherapy for Recurring Headache and Migraine Pain

Ross Hauser, MD, McCullough H. Dextrose prolotherapy for recurring headache and migraine pain. Practical Pain Management. June 2009:58-65.


This retrospective case series study revealed that Hackett-Hemwall dextrose prolotherapy appears to provide an effective, long-lasting treatment for recurring tension and migraine headache pain and their associated symptoms.

Headaches and migranes are a common occurrence and can be multi-factorial in origin with various triggers. It is thought that weak or loose neck ligaments and/or tendons may act as headache triggers in some people, validating the use of dextrose prolotherapy as a reasonable treatment option. To this end, the authors of this retrospective pilot study analyzed treatment of patients at the Beulah Land charity medical clinic which operated from 1994 to 2005 in Thebes, Illinois. The authors have done an excellent job of collecting and interpreting the data and discussing the issues in this most interesting study.

The results of this retrospective pilot study strongly suggest that Hackett-Hemwall dextrose prolotherapy can play a role in decreasing intensity level, frequency, duration, number of associated symptoms and light sensitivity in patients with headache and migraine pain. One-hundred percent of patients reported they were at least somewhat better after receiving Hackett-Hemwall dextrose prolotherapy, with 39% of these patients reporting 100% improvement. Forty-seven percent of patients stated the intensity of their pain was almost not noticeable after receiving treatment. Notable improvements in the duration of time they suffered from headache pain was also experienced after treatment. Seventy-three percent of patients reported a decreased sensitivity to light during a headache. Symptoms associated with tension and migraine headaches decreased in 80% of the patients in this study.

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